BIONATURE

BIONATURE, ISSN No. : 0970-9835 (Print), 0974-4282 (Online), Vol.: 37, Issue.: 2

Original Research Article

SICKLE CELL DISORDER: A FAMILY STUDY WITH EIGHT HOMOZYGOUS AND TWO HETEROZYGOUS CHILDREN

 

SUDAM L. KATE1, GUNVANT H. YEOLA1, PRASHANT N. DALVI1, GIRISH T. KULKARNI1, YOGESH S. PRABHUNE1 AND RUMA V. MANCHANDA2*

1Department of Sickle Cell, Maharashtra Arogya Mandal & Sumatibhai Shah Ayurved Mahavidyala, Hadapsar, Pune 411028, India.

2Department of Pathology, KEM Hospital, Rasta Peth, Pune 400011, India.

Abstracts

Sickle cell anaemia is a universal haemoglobin genetic disorder exhibiting segregation in many families but according to our find, this large family of eight homozygous cases, is the largest single family reported in the world literature.

Keywords :

Sickle cell disorder, rare family with many sicklers; need for counselling centres; Tribals need regular study; sickle ell syndrome; largest number with homozygotes in a family.